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St Johns Wort

Hypericum perforatum

Well-studied antidepressant herb with extreme CYP3A4 induction potential. Known to reduce efficacy of numerous pharmaceuticals including oral contraceptives, anticoagulants, and immunosuppressants.

Key Facts

Primary Use
Mood
Evidence Tier
1
Evidence Score
0.50 / 1.00
Typical Dosage
400 mg/day
Plant Family
Hypericaceae

Common Uses

Safety & Considerations

Contraindications
None documented for general adult use. Consult a clinician if pregnant, nursing, or on medication.
Drug Interactions
No major interactions documented. Always disclose herbal supplements to your prescribing physician.

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